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    ChemicalBook >> CAS DataBase List >>Tetrasodium pyrophosphate

    Tetrasodium pyrophosphate

    CAS No.
    Chemical Name:
    Tetrasodium pyrophosphate
    pyrophosphate;TSPP;SODIUM DIPHOSPHATE DECAHYDRATE;Anhydrous sodium pyrophosphate;pyro;SODIUM TETRAPYROPHOSPHATE;sodiumpyrophosphate[na4p2o7];tetrasodiumpyrophosphate,anhydrous;Nsc56751;SODIUM DI
    Molecular Formula:
    Molecular Weight:
    MDL Number:
    MOL File:
    MSDS File:
    Last updated:2023-08-15 17:37:19

    Tetrasodium pyrophosphate Properties

    Melting point 80 °C
    Boiling point 93.8 °C
    Density 2.53 g/mL at 25 °C(lit.)
    vapor pressure 0Pa at 20℃
    storage temp. Inert atmosphere,Room Temperature
    solubility H2O: 0.1 M at 20 °C, clear, colorless
    form Granular
    color White
    Specific Gravity 2.534
    Odor Odorless
    PH Range 10.3
    Water Solubility Soluble in water. Insoluble in ethyl alcohol.
    Sensitive Hygroscopic
    Merck 14,9240
    Exposure limits NIOSH: TWA 5 mg/m3
    Stability Stable. Incompatible with strong oxidizing agents.
    LogP -3.42
    CAS DataBase Reference 7722-88-5(CAS DataBase Reference)
    FDA 21 CFR 182.6787; 182.6789; 582.6787; 582.6789; 173.310; 175.210; 175.300; 181.29; 182.70
    Substances Added to Food (formerly EAFUS) SODIUM PYROPHOSPHATE
    SCOGS (Select Committee on GRAS Substances) Sodium pyrophosphate, tetrabasic
    EWG's Food Scores 1
    FDA UNII O352864B8Z
    EPA Substance Registry System Tetrasodium pyrophosphate (7722-88-5)


    Risk and Safety Statements

    Symbol(GHS)  GHS hazard pictograms
    Signal word  Danger
    Hazard statements  H318
    Precautionary statements  P280-P305+P351+P338
    Hazard Codes  Xi,Xn
    Risk Statements  36/37/38-41-22
    Safety Statements  26-36-39
    WGK Germany  3
    RTECS  UX7350000
    TSCA  Yes
    HS Code  28353990
    NFPA 704
    2 1

    Tetrasodium pyrophosphate price More Price(13)

    Manufacturer Product number Product description CAS number Packaging Price Updated Buy
    Sigma-Aldrich P8010 Sodium pyrophosphate tetrabasic ≥95% 7722-88-5 500g $48.8 2023-06-20 Buy
    Sigma-Aldrich P8010 Sodium pyrophosphate tetrabasic ≥95% 7722-88-5 2.5kg $225 2023-06-20 Buy
    Alfa Aesar 013439 Sodium pyrophosphate, anhydrous tech. 7722-88-5 250g $37.5 2023-06-20 Buy
    Alfa Aesar 013439 Sodium pyrophosphate, anhydrous tech. 7722-88-5 1kg $74 2023-06-20 Buy
    Alfa Aesar A17546 Sodium pyrophosphate 98% 7722-88-5 250g $37.4 2023-06-20 Buy
    Product number Packaging Price Buy
    P8010 500g $48.8 Buy
    P8010 2.5kg $225 Buy
    013439 250g $37.5 Buy
    013439 1kg $74 Buy
    A17546 250g $37.4 Buy

    Tetrasodium pyrophosphate Chemical Properties,Uses,Production


    Sodium pyrophosphate, also called Tetrasodium pyrophosphate or TSPP is used in the laboratory as a buffering agent. The compound has been shown to be useful in the preparation of an EDTA-sodium pyrophosphate extraction buffer for microcystin analysis of soil samples. Tetrasodium pyrophosphate is an odorless, white powder or granules. It is used in water softener, buffering agent, thickening agent, dispersing agent, wool de-fatting agent, metal cleaner, soap and synthetic detergent builder, general sequestering agent, in electrodeposition of metals. It also acts as a tartar control agent in toothpaste and dental floss. In addition, it is used as a chelating agent in antimicrobial studies. It is also used as a food additive in common foods such as chicken nuggets, crab meat and canned tuna.

    Chemical Properties

    Tetrasodium pyrophosphate is a white crystalline powder or colourless crystals with the formula Na4P2O7. It contains the pyrophosphate ion and sodium cation. Toxicity is approximately twice that of table salt when ingested orally. There is also a hydrated form, Na4P2O7.10H2O.
    Tetrasodium pyrophosphate
    Tetrasodium pyrophosphate is used as a buffering agent, an emulsifier, a dispersing agent, and a thickening agent, and is often used as a food additive. It is widely used as an emulsifying salt (ES) in process cheese. Common foods containing sodium pyrophosphate include chicken nuggets, marshmallows, pudding, crab meat, imitation crab, canned tuna, and soy-based meat alternatives and cat foods and cat treats where it is used as a palatability enhancer. It is the active ingredient in Bakewell, the substitute for baking powder's acid component marketed during shortages in World War II. It is also used in some common baking powders.


    Pharmaceutic aid.
    Tetrasodium pyrophosphate (Na4P2O7) is a non-toxic and biocompatible compound used as an electroactive media for exfoliation of the surface coating. It is also be used as an additive in the food industry.
    Na4P2O7 can be used as an inorganic additive to improve the stability and electrochemical performance of redox flow batteries.


    As a water softener; as a metal cleaner; as a dispersing and emulsifying agent.


    Tetrasodium Pyrophosphate is a coagulant, emulsifier, and sequestrant that is mildly alkaline, with a ph of 10. it is moderately soluble in water, with a solubility of 0.8 g/100 ml at 25°c. it is used as a coagulant in noncooked instant puddings to provide thicken- ing. it functions in cheese to reduce the meltability and fat separa- tion. it is used as a dispersant in malted milk and chocolate drink powders. it prevents crystal formation in tuna. it is also termed sodium pyrophosphate, tetrasodium diphosphate, and tspp.


    Tetrasodium pyrophosphate is formed when pure disodium hydrogen orthophosphate is heated to 500℃ for 5 hours. The product will contain better than 98 per cent Na4P2O7. Crystalline masses large enough for optical measurements are produced by heating in platinum to above the melting point of the tetrasodium pyrophosphate, 800°, and cooling slowly. Higher temperatures or longer heating times do not change the tetrasodium pyrophosphate, as this is the final product in the dehydration of disodium hydrogen orthophosphate.


    ChEBI: Sodium diphosphate is an inorganic sodium salt comprised of a diphosphate(4-) anion and four sodium(1+) cations. More commonly known as tetrasodium pyrophosphate, it finds much use in the food industry as an emulsifier and in dental hygiene as a calcium-chelating salt. It has a role as a food emulsifier, a chelator and a food thickening agent. It contains a diphosphate(4-).

    General Description

    Odorless, white powder or granules. Mp: 995°C. Density: 2.53 g cm-3. Solubility in water: 3.16 g / 100 mL (cold water); 40.26 g / 100 mL boiling water. Used as a wool de-fatting agent, in bleaching operations, as a food additive. The related substance Tetrasodium pyrophosphate decahydrate (Na4P2O7 0H2O) occurs as colorless transparent crystals. Loses its water when heated to 93.8°C.

    Reactivity Profile

    Tetrasodium pyrophosphate is basic. Reacts exothermically with acids. Incompatible with strong oxidizing agents. Decomposes in ethyl alcohol.


    Toxic by inhalation.

    Health Hazard

    Tetrasodium pyrophosphate (TSPP) is of low toxicity, but the dust may be irritating to the eyes, upper respiratory tract, and skin. Mild to moderate skin and eye irritation have occurred with acute exposure to the dust.

    Safety Profile

    Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. It is not a cholinesterase inhibitor. When heated to decomposition it emits toxic fumes of POx and Na2O.

    Global( 467)Suppliers
    Supplier Tel Email Country ProdList Advantage
    Chongqing Chuandong Chemical (Group) Co. Ltd.
    +86-13637972665 +86-13637972665 wxc@cd1958.com China 81 58
    Wuhan Pinestone Fortune International Trading Co., Ltd.
    +86-027-85615902 +86-13971435335 imp.exp8@fengfan.net China 29 58
    Jiangsu Kolod Food Ingredients Co.,Ltd.
    +86-518-85110578 +8618805133257 sales3257@jskolod.com China 130 60
    Henan Tianfu Chemical Co.,Ltd.
    +86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21722 55
    Hefei TNJ Chemical Industry Co.,Ltd.
    +86-0551-65418679 +86-18949832763 info@tnjchem.com China 2990 55
    career henan chemical co
    +86-0371-86658258 sales@coreychem.com China 29922 58
    Hubei Jusheng Technology Co.,Ltd.
    18871490254 linda@hubeijusheng.com CHINA 28183 58
    Hebei Guanlang Biotechnology Co., Ltd.
    +86-19930503282 alice@crovellbio.com China 8836 58
    Chongqing Chemdad Co., Ltd
    +86-023-61398051 +8613650506873 sales@chemdad.com China 39919 58
    Shaanxi Dideu Medichem Co. Ltd
    +8618192503167 1006@dideu.com China 3965 58

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    View Lastest Price from Tetrasodium pyrophosphate manufacturers

    Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
    Tetrasodium pyrophosphate pictures 2023-08-15 Tetrasodium pyrophosphate
    US $0.00-0.00 / kg 1kg 0.99 50000kg Hebei Yibangte Import and Export Co. , Ltd.
    Tetrasodium pyrophosphate pictures 2023-03-06 Tetrasodium pyrophosphate
    US $2.60 / KG 1KG 99.5% 5000kg Hebei Crovell Biotech Co Ltd
    Tetrasodium pyrophosphate pictures 2023-02-01 Tetrasodium pyrophosphate
    US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
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